Top 12 Venture Capital Firms for B2B Startups To Knw

For founders in the business-to-business space, preparing to raise capital means more than just perfecting your pitch. It means finding investors who truly understand your market, whether you're building enterprise technology or a specific SaaS solution.

To help you focus your search, our team has curated this guide to some of the top B2B focused VC firms. Think of it as a starting point for identifying the right partners for your company's next stage of growth.

Actively raising? You can now access non-dilutive funding options like venture debt and credit lines through Rho Capital. Rho provides access to business banking, corporate cards, and bill pay—built for startup teams moving fast.

Key Takeaways

• Securing venture funding provides more than capital; it gives you a strategic partner with deep expertise in the business-to-business market.

• VCs like Work-Bench, MissionOG, Storm Ventures, and Mighty Capital are notable backers in the B2B space, actively investing in startups and small businesses.

• If you're raising or have just closed a round, Rho helps you manage your new capital with fast business banking, corporate cards, and integrated bill pay.

Which VC Firms in B2B Are Right for Your Stage?

From the earliest stages of your company to planning an exit, it's helpful to know who to talk to. We've created this overview to show which B2B VC firms invest at each stage.

Pre-seed and Seed VC Firms in B2B

This initial funding stage is for founders developing a core idea and building a minimum viable product. Some B2B-focused VC firms active at this stage include New York-based Work-Bench and 2048 Ventures, along with Zane Venture Fund.

If you're looking for alternatives to equity financing, Rho Capital connects startups to non-dilutive funding options such as venture debt and credit lines through a fast, guided matching process.

Early Stage VC Firms in B2B

Early-stage funding, such as Series A or B, helps you scale operations once you have a proven product and market traction. Enterprise technology VC firms like Storm Ventures and Cervin Ventures are known for their early-stage B2B investments, as is Mighty Capital.

Once funding is secured, Rho’s integrated financial tools—including business banking, corporate cards, and automated bill pay—help startups manage and deploy capital efficiently.

Late Stage VC Firms in B2B

Late-stage capital is for established companies preparing for major expansion, a potential acquisition, or an IPO. For founders at this point, firms like MissionOG and Wildcat Venture Partners provide capital for growth-stage B2B technology companies.

It's also worth noting that many venture capital firms invest across multiple stages, from seed to exit.

To help you find the right investment partner, here is a closer look at some of the top VC firms focused on the B2B space. We've gathered key details on their investment stages, geographic focus, and what makes each firm a compelling choice for founders.

1. Work-Bench

Based in New York City, Work-Bench is a venture capital firm that concentrates on early-stage enterprise software companies. They primarily invest at the seed stage, providing foundational support for B2B startups.

The firm's dedication to enterprise technology is a key characteristic, backing companies that build complex solutions for businesses. Their portfolio includes successful companies like the digital identity platform Socure and the mental health provider Spring Health.

Work-Bench is a strong potential partner if you are a founder building an enterprise software company and seeking seed funding. For founders exploring all their financing options, Rho Capital can also connect you to non-dilutive funding like venture debt and credit lines.

• Investment stages: Seed and early-stage venture
• Industries of focus: Enterprise software, B2B, SaaS, financial services
• Geographical presence: New York, New York
• Founded: 2013
• Notable portfolio companies: Socure, Spring Health, Cockroach Labs, VTS

You can refer to their website here.

2. MissionOG

Based in Philadelphia, MissionOG provides capital to B2B technology companies in both their early and growth stages. For founders exploring all their financing options, Rho Capital can also connect you to non-dilutive funding like venture debt and credit lines.

The firm has a strong focus on B2B technology, particularly within financial services and SaaS. Notable investments include the AI fraud-detection company Featurespace and Venminder, a third-party risk management platform.

MissionOG could be a good partner if you are a founder of a B2B technology company, especially in fintech, with a proven business model ready for growth. Once funding is secured, Rho’s integrated financial tools help you manage and deploy capital efficiently.

• Investment stages: Early and late-stage venture
• Industries of focus: B2B technology, financial services
• Geographical presence: Philadelphia, Pennsylvania
• Founded: 2012
• Notable portfolio companies: Venminder, Deko, iDonate, Featurespace, Autobooks
• Number of investments: 68

You can refer to their website here.

3. Storm Ventures

Based in Menlo Park, Storm Ventures is a venture capital firm that invests exclusively in early-stage enterprise technology companies. With a history dating back to 1997, they have a long track record of backing B2B startups from their initial stages.

The firm’s defining feature is its singular focus on the enterprise sector, backing companies from seed to early-stage. Their portfolio includes major successes like marketing automation platform Marketo and sales CRM Pipedrive, demonstrating their ability to identify future market leaders.

Storm Ventures is a great fit if you're an early-stage founder building a B2B software or fintech company with high-growth potential. If you're also considering non-dilutive options, Rho Capital can connect you with venture debt and credit lines to complement your equity round.

• Investment stages: Seed, early-stage, and late-stage venture
• Industries of focus: B2B, enterprise software, financial services, fintech
• Geographical presence: Menlo Park, California
• Founded: 1997
• Notable portfolio companies: Talkdesk, Pipedrive, Marketo, MobileIron
• Number of investments: 278
• Number of exits: 66

You can refer to their website here.

4. Mighty Capital

Mighty Capital is an early-growth venture firm in San Francisco that invests in companies where product is a key driver of success. They focus on seed and early-stage rounds, providing capital to help founders scale their operations.

The firm has a distinct product-centric approach, backing founders who build businesses with strong product-led growth models. Their portfolio includes major exits like Airbnb and Amplitude, showing their ability to support companies through to public markets.

Mighty Capital is a strong match if you are a founder building a product-focused B2B company and are ready for early-stage growth. Once you secure funding, our integrated platform at Rho helps you manage your new capital with business banking, corporate cards, and automated payments.

• Investment stages: Seed and early-stage venture
• Industries of focus: B2B, Enterprise Software, Product Management
• Geographical presence: San Francisco, California
• Founded: 2017
• Notable portfolio companies: Airbnb, Amplitude, DigitalOcean, Cameo, Netskope
• Number of investments: 33
• Number of exits: 10

You can refer to their website here.

5. Zane Venture Fund

Based in Atlanta, Zane Venture Fund invests in early-stage, tech-enabled companies. The firm has a specific mission to back high-growth startups led by founders from underrepresented backgrounds.

Their focus is on "the Future of Health," which includes healthcare, wellness, and nutrition, but they also invest in sectors like EdTech and B2B SaaS. Notable investments like the digital health marketplace MDisrupt and workforce development platform SkillCycle show their commitment to both social impact and scalable technology.

Zane Venture Fund is a strong match if you're an early-stage founder, particularly from an overlooked background, building a tech solution in their focus areas. For founders exploring all financing options, Rho Capital can also connect you to non-dilutive funding like venture debt and credit lines.

• Investment stages: Seed and early-stage venture
• Industries of focus: Health Care, Wellness, EdTech, B2B, SaaS
• Geographical presence: Atlanta, Georgia
• Founded: 2019
• Notable portfolio companies: MDisrupt, SkillCycle, Freeing Returns, ConConnect
• Number of investments: 20

You can refer to their website here.

6. Branded Hospitality

Branded Hospitality is a New York-based investment firm that backs companies at the intersection of hospitality, media, and technology. They invest across various stages, from seed and early-stage venture to private equity, supporting businesses as they grow.

The firm's clear focus is on technology that modernizes the hospitality and restaurant industries. Their portfolio includes companies like Bbot, a mobile payment platform acquired by DoorDash, and PourMyBeer, a self-serve beverage technology.

Branded Hospitality is a good fit if you're a founder building a B2B or consumer-facing business in the food, beverage, or retail tech sectors. For founders exploring all their financing options, Rho Capital can also connect you to non-dilutive funding like venture debt and credit lines.

• Investment stages: Seed, early-stage venture, private equity
• Industries of focus: Hospitality, food and beverage, retail technology, B2B, SaaS
• Geographical presence: New York, New York
• Founded: 2017
• Notable portfolio companies: Bbot, PourMyBeer, Ottonomy IO, Chowly, Big Chicken
• Number of investments: 73
• Number of exits: 8

You can refer to their website here.

7. 2048 Ventures

Based in New York, 2048 Ventures is a thesis-driven firm that backs companies at the pre-seed and seed stages. They focus on founders building businesses that use technology to solve significant real-world problems.

The firm's approach is centered on backing founders with deep technical or scientific expertise. Their portfolio includes the drone startup Aerodome, which had a major exit, and beauty-services SaaS platform GlossGenius.

2048 Ventures is a good match if you are a founder with a strong technical background in areas like AI, robotics, or biotech. For founders exploring all financing options, Rho Capital can also connect you to non-dilutive funding like venture debt and credit lines.

• Investment stages: Seed and early-stage venture
• Industries of focus: Artificial Intelligence (AI), B2B, Biotechnology, Health Care, Machine Learning, Robotics, SaaS
• Geographical presence: New York, New York
• Founded: 2019
• Notable portfolio companies: Aerodome, GlossGenius, Soona, Nomic Bio, Vitally
• Number of investments: 136
• Number of exits: 2

You can refer to their website here.

8. Golden Section

Golden Section, based in Houston, operates as both a founder's studio and a venture capital fund. The firm partners with B2B SaaS companies at the pre-seed and seed stages, providing capital and hands-on support.

A key aspect of their model is the founder's studio, which offers direct operational support in product development and go-to-market strategy. This "build with you" approach provides founders with a team of operators and a network of experts to help scale their business.

Golden Section is a great choice for early-stage B2B SaaS founders who are looking for a hands-on partner to help build their company from the ground up. For founders exploring all their financing options, Rho Capital can also connect you to non-dilutive funding like venture debt and credit lines.

• Investment stages: Seed, early-stage venture, debt
• Industries of focus: B2B, SaaS, Software
• Geographical presence: Houston, Texas
• Founded: 2012
• Notable portfolio companies: Podetize, Avise, Upkey
• Number of investments: 41
• Number of exits: 1

You can refer to their website here.

9. Cervin Ventures

Cervin Ventures is an early-stage venture capital firm based in Palo Alto, focused on B2B technology companies. They partner with founders to help build their startups into successful, lasting businesses.

The firm concentrates on enterprise software and financial services, with a history of backing companies to significant outcomes. Their portfolio includes major exits like the customer loyalty platform Punchh and the coding education platform Tynker.

Cervin Ventures is a solid choice if you are an early-stage founder in the B2B software sector seeking a partner with deep enterprise experience. Once you secure funding, our integrated platform at Rho helps you manage your new capital with business banking, corporate cards, and automated payments.

• Investment stages: Seed, early-stage, and late-stage venture
• Industries of focus: B2B, Enterprise Software, Financial Services
• Geographical presence: Palo Alto, California
• Founded: 2011
• Notable portfolio companies: LaunchDarkly, Punchh, EdCast, Tynker, Celona
• Number of investments: 85
• Number of exits: 15

You can refer to their website here.

10. Upekkha Vertical AI Accelerator

Upekkha is a venture firm and accelerator that helps Indian founders build global B2B SaaS companies. They invest at the seed and early stages, providing both capital and structured support for international growth.

The firm's approach is centered on "Vertical AI," backing companies that apply artificial intelligence to solve problems in specific industries. Their portfolio includes companies like the skills platform iMocha and HR tech firm Talview, showing their commitment to this thesis.

Upekkha is a strong choice if you are an Indian founder of an early-stage, AI-driven B2B SaaS company with global ambitions. For founders exploring all their financing options, Rho Capital can also connect you to non-dilutive funding like venture debt and credit lines.

• Investment stages: Seed, early-stage venture
• Industries of focus: B2B, SaaS, Enterprise Software, Vertical AI
• Geographical presence: San Francisco, California (with a focus on Indian founders)
• Founded: 2017
• Notable portfolio companies: Spyne, Talview, iMocha, Classpro
• Number of investments: 114

You can refer to their website here.

11. Signia Venture Partners

Signia Venture Partners is an early-stage firm based in Redwood City that backs founders building what they call "world-changing companies." They primarily invest at the seed and early stages, providing capital to help entrepreneurs get their ideas off the ground.

The firm's portfolio shows a clear interest in companies applying advanced technology to solve major problems, from climate tech to digital health. Notable investments include Atmo, an AI-powered weather forecasting platform, and Kintsugi, which uses voice analysis to detect signs of depression.

Signia could be a good partner if you are a founder with a bold, tech-driven vision and are seeking early-stage capital. For founders exploring all their financing options, Rho Capital can also connect you to non-dilutive funding like venture debt and credit lines.

• Investment stages: Seed, early-stage venture, debt
• Industries of focus: B2B, Finance, Climate Tech, Digital Health
• Geographical presence: Redwood City, California
• Founded: 2012
• Notable portfolio companies: Inertia Systems, Atmo, Kintsugi
• Number of investments: 117
• Number of exits: 28

You can refer to their website here.

12. Wildcat Venture Partners

Wildcat Venture Partners is a San Mateo-based firm that invests in early-stage B2B and B2B2C technology startups. They provide capital from seed to later stages, focusing on companies in markets like digital health, EdTech, and FinTech.

The firm has a track record of backing companies to major exits, including the marketing automation platform Marketo, which was purchased by Adobe, and the online lending platform Kabbage, acquired by American Express. This history signals their ability to support companies with high-growth ambitions.

Wildcat is a good fit for founders building B2B technology companies in their key sectors who are aiming for a significant scale-up and exit. Once you secure funding, our integrated platform at Rho helps you manage your new capital with business banking, corporate cards, and automated payments.

• Investment stages: Seed, early-stage, and late-stage venture
• Industries of focus: B2B, Enterprise SaaS, FinTech, EdTech, Digital Health
• Geographical presence: San Mateo, California
• Founded: 2015
• Notable portfolio companies: Kabbage, Marketo, Rocket Fuel, Ticketfly, Workday
• Number of investments: 39
• Number of exits: 12

You can refer to their website here.

What This Tells Us About The VC Scene for B2B Companies

This overview of venture capital firms shows a healthy and varied funding environment for B2B founders. There is strong support for early-stage companies, but you can find dedicated partners from pre-seed development all the way to late-stage growth. This balance gives you options, no matter where you are in your company's lifecycle.

Geographically, while investors are concentrated in major tech hubs like New York and the Bay Area, firms in cities like Atlanta and Houston show that opportunities are not limited to the coasts. This variety means you can be more selective in finding a partner who aligns with your specific goals.

As you plan your next steps, remember that equity is just one part of the funding equation. Our team at Rho can also connect you to non-dilutive financing through Rho Capital, helping you build a capital stack that fits your business.

Raise Confidently with Rho

When you're raising capital, your time is your most valuable asset. A focused list of investors who understand your market helps you direct your energy where it counts.

If you’re seeking funding, Rho Capital connects you to non-dilutive funding options like venture debt and credit lines through a fast, guided process. We help you find the right financing without chasing down lenders.

Our team helps you access financing options like venture debt and working capital that fit your business. Once capital is secured, Rho provides integrated tools—business banking, corporate cards, and automated bill pay—to help you manage and deploy funds efficiently.

FAQs about Venture Capital Firms Focused on B2B

What are micro VC firms?

Micro VCs are smaller venture capital funds, typically investing at the pre-seed and seed stages. They write smaller checks than larger firms but often provide focused, hands-on support, making them a great option for very early-stage B2B companies.

Are there B2B venture capital firms in Europe?

Yes, Europe has a growing number of B2B focused VC firms, especially in hubs like London, Berlin, and Paris. Many specialize in SaaS and fintech, offering capital and support for founders expanding into European markets.

Which Canadian cities are hubs for tech VC firms?

Toronto, Vancouver, and Montreal are major hubs for Canadian tech venture capital. These cities have strong ecosystems supporting B2B startups in areas like AI and SaaS, with many firms actively investing in early-stage companies.

How do I choose the right early-stage VC firm?

Look for a firm with a portfolio and expertise that align with your industry. Consider their network and the hands-on support they offer. It's also wise to explore non-dilutive options like those offered through Rho Capital to complement your round.

What do SaaS venture capital firms look for?

SaaS VCs typically look for strong recurring revenue, low customer churn, and a clear go-to-market strategy. Once you secure funding, our tools at Rho help you manage cash flow and payments to support your growth.

How can Rho help my B2B startup with funding?

Our team helps you prepare for and manage your fundraising. Rho Capital connects you with non-dilutive financing, while our integrated platform helps you manage new capital with banking, corporate cards, and automated payables.