Top 14 Venture Capital Firms for Enterprise Startups

When you're preparing to raise capital, knowing which investors truly understand your business is critical. For founders in Enterprise software and SaaS, this means finding partners who appreciate the specific challenges and opportunities of your model.

To help you focus your fundraising efforts, our team put together this overview of top venture capital firms that invest in Enterprise technology. This guide gives you a quick, clear picture of the key players so you can find the right fit.

Actively raising? You can now access non-dilutive funding options like venture debt and credit lines through Rho Capital. Rho provides access to business banking, corporate cards, and bill pay—built for startup teams moving fast.

Key Takeaways

• Securing venture funding provides Enterprise startups with not only capital but also strategic partners who understand the specific challenges of the sector.
• Venture firms specializing in Enterprise technology, such as Glasswing Ventures, LRVHealth, M25, and G20 Ventures, are notable backers for startups in this space.
• For leaders raising or managing a new round, Rho helps you control your capital with integrated business banking, corporate cards, and bill pay.

Which VC Firms in Enterprise Are Right for Your Stage?

Whether you're an early-stage founder or preparing for an exit, it helps to know which investors to approach. Here’s a quick look at venture capital firms that invest in Enterprise companies, organized by stage.

Pre-seed and Seed VC Firms in Enterprise

Pre-seed and seed funding are the first institutional checks, designed to help you validate an idea and build your initial product. For founders building enterprise software, some SaaS focused VC firms to consider include Chicago-based M25, which is highly active in the Midwest, and Frontures, a San Francisco venture capital firm focused on this stage.

Early Stage VC Firms in Enterprise

Early-stage funding, like Series A and B, is meant to help you scale operations and grow your customer base after finding product-market fit. Among the many Boston venture capital firms, Glasswing Ventures concentrates on AI for the enterprise, while Brick & Mortar Ventures is one of the leading software venture capital firms for the construction industry.

Once you secure a new round, managing that capital efficiently is the next step. Rho’s integrated platform helps with business banking, corporate cards, and automated bill pay, giving you full control over your new funds.

Late Stage VC Firms in Enterprise

Late-stage venture capital is for established companies looking to accelerate growth, enter new markets, or prepare for an M&A event or IPO. These enterprise technology venture capital firms include Dell Technologies Capital, the corporate VC arm of Dell based in Silicon Valley, and Expansion Venture Capital, one of the active New York venture capital firms.

As you approach these later stages, you may also want to explore non-dilutive financing. Rho Capital connects startups to options like venture debt and credit lines through a fast, guided process, helping you access capital tailored to your business model.

Finally, remember that many venture capital firms for startups, such as PJC and Lumia Capital, invest across multiple stages from seed to growth.

Below is a closer look at top VC firms that focus on the Enterprise sector. We've included key details on their investment stages, geographic focus, and what makes each firm a strong potential partner for founders.

1. Glasswing Ventures

Based in Boston, Glasswing Ventures is an early-stage firm that invests in startups applying artificial intelligence and frontier technology to enterprise and cybersecurity markets.

The firm shows a clear focus on AI's application in business, with portfolio companies like Black Kite for cyber-risk monitoring and Zylotech, a B2B data platform acquired by Terminus.

Glasswing is a strong potential partner if you are a founder with deep technical expertise building AI-powered software for complex enterprise or security challenges.

Once you secure funding, Rho’s integrated platform helps with business banking, corporate cards, and automated bill pay, giving you full control over your new funds.

• Investment stages: Seed, Early Stage Venture
• Industries of focus: Artificial Intelligence, Enterprise Software, Cybersecurity
• Geographical presence: Boston, MA
• Founded: 2016
• Notable investments: Allure Security, Basetwo AI, ChaosSearch

You can refer to their website here.

2. LRVHealth

LRVHealth is a Boston-based venture capital firm that has been investing in healthcare technology since 2000. Their team is composed of experienced healthcare investors, operators, and advisors, giving them an "inside healthcare" perspective on the market.

The firm focuses on enterprise solutions that improve healthcare delivery, with notable investments in patient engagement and data interoperability. Their portfolio includes successes like the patient-intake platform Phreesia, which went public, and Current Health, a remote patient-monitoring startup acquired by Best Buy.

LRVHealth is a strong match for founders building enterprise technology for the healthcare market, particularly those who value a partner with deep operational experience. The firm invests across seed, early, and late stages, offering support throughout a company's growth.

As you scale your healthcare startup, managing your finances becomes crucial. Rho’s integrated platform helps with business banking, corporate cards, and automated bill pay, giving you full control over your funds.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture
• Industries of focus: Health Care, Enterprise, Medical Device, Security
• Geographical presence: Boston, MA
• Founded: 2000
• Notable investments: Carevive, Current Health, Phreesia

You can refer to their website here.

3. M25

M25 is a Chicago-based venture capital firm known as one of the most active early-stage investors for startups headquartered in the Midwest. The firm invests across a broad range of industries, demonstrating a strong commitment to fostering growth in the regional tech ecosystem.

The firm invests across sectors including Enterprise Software and FinTech, with a portfolio that highlights its ability to back high-growth companies. Notable investments include the home-insurance unicorn Kin Insurance and successful exits like the acquisition of Pactsafe by Ironclad.

M25 is a strong potential partner for founders based in the Midwest who are building at the seed or early stages. Their industry-agnostic approach makes them a good fit for many business models, particularly for companies in the enterprise and fintech spaces.

Once you secure funding, Rho’s integrated financial tools—including business banking, corporate cards, and automated bill pay—help you manage and deploy capital efficiently.

• Investment stages: Seed, Early Stage Venture
• Industries of focus: Enterprise Software, FinTech, Consumer
• Geographical presence: Chicago, IL (invests across the Midwest)
• Founded: 2015
• Notable investments: Kin Insurance, Loop Returns, Branch

You can refer to their website here.

4. G20 Ventures

G20 Ventures is a Boston-based firm that invests from seed to late stage. They position themselves as a capital partner for Web3 communities, with a portfolio that also includes enterprise and consumer technology.

The firm has a history of backing companies to successful exits, including the cloud communications platform Fuze and the desktop-virtualization company Frame. Their investments show a focus on enterprise solutions alongside their interest in Web3.

G20 Ventures could be a good fit if you're building in the Web3 space or developing enterprise software with a clear path to market. As you manage your growth, Rho’s integrated platform helps with business banking, corporate cards, and automated bill pay, giving you full control over your capital.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture
• Industries of focus: Web3, Enterprise, Consumer, Information Technology
• Geographical presence: Boston, MA
• Founded: 2013
• Notable investments: Fuze, Frame, Congruity360

You can refer to their website here.

5. Brick & Mortar Ventures

Based in San Francisco, Brick & Mortar Ventures invests in early-stage companies developing software and hardware for the construction and real estate industries. The firm is known for its deep focus on "ConTech," with a portfolio of major exits including PlanGrid, which was acquired by Autodesk for $875 million.

Founders building technology to modernize the built world will find a knowledgeable partner in this firm. Once you secure funding, Rho’s integrated financial tools—including business banking, corporate cards, and automated bill pay—help you manage and deploy capital efficiently.

• Investment stages: Seed, Early Stage Venture
• Industries of focus: Construction, Architecture, Engineering, Enterprise Software, Hardware
• Geographical presence: San Francisco, CA
• Founded: 2015
• Notable exits: PlanGrid, BuildingConnected, Fieldwire, HoloBuilder

You can refer to their website here.

6. PJC

PJC is a Boston-based venture capital firm that has been investing since 2001. The firm supports companies from seed to late stage, with a focus on enterprise, consumer, and artificial intelligence.

The firm has a strong record of high-profile exits, including Nest's acquisition by Google and Expensify's IPO. This history demonstrates their ability to back both consumer and enterprise companies through to major growth milestones.

PJC is a strong potential partner for founders building in AI, enterprise, or consumer technology with a clear vision for scale. As you grow, Rho’s integrated platform helps with business banking, corporate cards, and automated bill pay, giving you full control over your funds.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture
• Industries of focus: Artificial Intelligence, Consumer, Enterprise, FinTech, InsurTech
• Geographical presence: Boston, MA
• Founded: 2001
• Notable exits: Nest (acquired by Google), Expensify (IPO), Appcast (acquired by StepStone)

You can refer to their website here.

7. Capital One Ventures

Capital One Ventures is the corporate venture arm of Capital One, making strategic investments in companies shaping the future of data, technology, and financial services. Based in San Francisco, the firm supports startups from seed to late stage.

The firm's portfolio highlights its focus on high-growth companies, with major successes like the data platform Snowflake and the B2B payments company Melio. This track record shows a clear interest in backing businesses that can achieve significant scale in markets like FinTech, enterprise AI, and cloud infrastructure.

Capital One Ventures is a strong potential partner for founders building technology in data, finance, or enterprise software who are looking for a strategic investor. As you prepare for growth, Rho Capital can connect you to non-dilutive funding options like venture debt and credit lines to complement your equity round.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture
• Industries of focus: FinTech, Enterprise, Big Data, Cloud Infrastructure, B2B
• Geographical presence: San Francisco, CA
• Founded: 2014
• Notable investments: Snowflake, MoneyLion, Glean, Aqua Security

You can refer to their website here.

8. Frontures

Frontures is a San Francisco-based venture capital firm that concentrates on pre-seed and seed-stage investments. Founded in 2019, it backs companies in the enterprise, blockchain, and internet sectors.

The firm focuses on foundational technologies, backing companies that are building complex solutions from the ground up. Its portfolio includes 3DOS, a decentralized 3D-printing network, and Jacobi Robotics, a startup making industrial robots easier to program, which PitchBook reports was a recent seed investment.

Frontures is a strong match for technical founders at the earliest stages who are building companies in complex fields. Their dedicated focus on seed rounds suggests they are prepared to partner with new ventures from the very beginning.

Once you secure your seed funding, Rho’s integrated financial tools—including business banking, corporate cards, and automated bill pay—help you manage and deploy capital efficiently.

• Investment stages: Seed
• Industries of focus: Enterprise, Blockchain, Internet
• Geographical presence: San Francisco, CA
• Founded: 2019
• Notable investments: Jacobi Robotics, 3DOS, Kanari AI, Neuronix AI Labs

You can refer to their website here.

9. Dell Technologies Capital

Dell Technologies Capital is the corporate venture arm of Dell, investing from its base in Palo Alto. The firm backs companies building foundational technologies in enterprise and cloud infrastructure.

The firm has a strong history of backing companies to major exits, including the acquisitions of Adallom by Microsoft and Barefoot Networks by Intel. This track record points to a focus on deep-tech startups with clear strategic value to larger players.

Dell Technologies Capital is a good match for founders developing enterprise infrastructure or security software. The firm offers a path to significant scale and strategic connections within the industry.

As you approach later stages with a strategic partner like Dell, you may also want to explore non-dilutive financing. Rho Capital connects startups to options like venture debt and credit lines through a fast, guided process, helping you access capital tailored to your business model.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture
• Industries of focus: Cloud Infrastructure, Enterprise, Software, Financial Services
• Geographical presence: Palo Alto, CA
• Founded: 2012
• Notable exits: Adallom (acquired by Microsoft), Barefoot Networks (acquired by Intel), Arista Networks (IPO)

You can refer to their website here.

10. Sputnik ATX

Sputnik ATX is an Austin-based venture fund and startup accelerator that focuses on backing "maker-founders." The firm combines capital with a hands-on program to help early-stage companies build and scale their operations.

The firm invests across a wide range of industries, from enterprise software and IT to consumer brands in beauty and fashion. Their portfolio includes companies like the reg-tech platform Cognitive View and the AI-driven freight platform Kargoplex, showing a focus on founders solving specific problems.

Sputnik ATX is a strong match for early-stage founders who are deeply involved in building their product and value an accelerator environment. As you grow with their support, Rho’s integrated financial tools—including business banking, corporate cards, and automated bill pay—help you manage and deploy capital efficiently.

• Investment stages: Seed, Early Stage Venture
• Industries of focus: Enterprise, IT Management, Retail, Social, Gaming, Fashion
• Geographical presence: Austin, TX
• Founded: 2017
• Notable investments: Cognitive View, Kargoplex, Lodgeur, LAMIK

You can refer to their website here.

11. Expansion Venture Capital

Expansion Venture Capital is a New York-based firm that provides capital and mentorship to companies from their early stages through to growth rounds. They invest across a wide range of industries, backing founders who are building for significant scale.

The firm has a clear track record of backing high-profile companies that achieve "unicorn" status and successful public-market debuts. Their portfolio includes major names like the insurance platform Lemonade and the equity management tool Carta, signaling a focus on businesses with the potential for massive market adoption.

Expansion VC is a strong potential partner for founders with a clear vision for building a category-defining company. As you scale toward these later stages, Rho Capital can help you access non-dilutive funding like venture debt to complement your equity rounds, giving you more flexibility without further dilution.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture
• Industries of focus: Enterprise, FinTech, Consumer, InsurTech, Real Estate
• Geographical presence: New York, NY
• Founded: 2010
• Notable investments: Turo, Allbirds, ClassPass

You can refer to their website here.

12. Tech Square Ventures

Tech Square Ventures is an Atlanta-based firm that invests in seed and early-stage companies. They focus on enterprise software, marketplace platforms, and tech-enabled services, backing founders from the beginning.

The firm supports companies building practical solutions for large markets, from enterprise sales tools like Saleo to critical logistics tech like Coros. Their portfolio also includes companies tackling big challenges in climate tech and workforce training, showing a focus on impactful, scalable technology.

Tech Square Ventures is a good fit for early-stage founders building enterprise or platform companies, particularly those based in the Southeast. Once you secure that early funding, Rho’s integrated platform helps with business banking, corporate cards, and automated bill pay, giving you full control over your new funds.

• Investment stages: Seed, Early Stage Venture
• Industries of focus: Enterprise Software, Marketplace, Platform Technology, Logistics
• Geographical presence: Atlanta, GA
• Founded: 2014
• Notable investments: Saleo, Coros, Moth + Flame

You can refer to their website here.

13. Zeno Partners

Zeno Partners, through its venture arm Zeno Ventures, is a San Francisco-based firm that backs technology companies. They invest from seed to late stage across both consumer and enterprise markets.

The firm's portfolio features high-growth companies, including the fintech platform Mercury and autonomous-vehicle software unicorn Applied Intuition. This signals a focus on backing businesses with the potential for significant market leadership in large, technical sectors.

Zeno Partners is a good match for founders building ambitious companies in enterprise or consumer tech with a clear path to scale. As you manage your growth, Rho’s integrated platform helps with business banking, corporate cards, and automated bill pay, giving you full control over your capital.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture
• Industries of focus: Enterprise, Consumer, Financial Services, Technology
• Geographical presence: San Francisco, CA
• Founded: 2016
• Notable investments: Applied Intuition, Mercury, AvantStay, BioRender

You can refer to their website here.

14. Lumia Capital

Lumia Capital is an expansion-stage venture firm that partners with companies ready for significant growth. Based in San Francisco, they specialize in helping US and European innovators expand into international markets.

The firm has a strong record in SaaS and FinTech, backing companies to major outcomes. Notable exits include the ride-hailing service Careem, acquired by Uber, and the incident-response platform PagerDuty, which had a successful IPO.

Lumia Capital is a good fit for founders who have established their product and are looking for a partner to help scale globally. Their focus on international expansion makes them a strategic choice for companies with global ambitions.

As you plan for this level of expansion, Rho Capital can connect you to non-dilutive funding options like venture debt, helping you finance growth without giving up more equity.

• Investment stages: Early Stage Venture, Late Stage Venture
• Industries of focus: Enterprise, SaaS, FinTech, Retail Technology
• Geographical presence: San Francisco, CA
• Founded: 2011
• Notable exits: Careem (acquired by Uber), PagerDuty (IPO), Kabbage (acquired by American Express)

You can refer to their website here.

What This Tells Us About The VC Scene for Enterprise Companies

This overview shows that the investment community for enterprise technology is both broad and deep. You’ll find a healthy mix of firms that focus on early-stage companies and those that invest across all stages, providing a clear path for growth from seed to exit. This suggests a stable, mature sector with consistent opportunities for founders.

Geographically, while major hubs like San Francisco and Boston are prominent, strong investors are active in cities across the country, from Chicago to Atlanta. This diversity means you can often find a great partner without having to relocate. The key is to find a firm whose stage, industry focus, and expertise align with your company’s needs.

As you weigh your equity options, remember that non-dilutive funding can also play a role. Rho Capital helps founders access financing like venture debt, which can complement your fundraising efforts without requiring you to give up more of your company.

Raise Confidently with Rho

Fundraising requires your full attention, and a focused list of relevant investors is one of your most valuable assets. It allows you to direct your energy toward the partners who truly understand your business and stage of growth.

If you are actively raising, Rho Capital connects you to non-dilutive funding options like venture debt and credit lines through a fast, guided process. We help you access financing tailored to your business model without chasing lenders.

Once your capital is secured, our integrated platform provides the tools you need to manage it. With business banking, corporate cards, and automated bill pay in one place, you can deploy your funds with confidence.

FAQs about Venture Capital Firms Focused on Enterprise

Which European venture capital firms focus on Enterprise SaaS?

Many European VCs, like London's Accel or Berlin's Point Nine, actively back enterprise software companies. They seek strong product-market fit and a clear strategy for scaling across different markets, with a focus on sustainable growth models.

Are there active Asia venture capital firms for enterprise startups?

Yes, firms in hubs like Singapore and Hong Kong are increasingly investing in enterprise technology. They often look for companies with solutions tailored to regional market needs and the potential for cross-border expansion within Asia.

What do growth stage venture capital firms look for in an enterprise company?

Growth stage investors want to see proven traction, a repeatable sales model, and strong unit economics. You should be prepared to show consistent revenue growth and a clear plan for capturing a larger market share.

What are my funding options beyond equity from SaaS VC firms?

Beyond equity, you can explore non-dilutive financing. Rho Capital connects you with options like venture debt and credit lines, which provide capital for growth without giving up more ownership in your company or signing legacy terms.

How can Rho help me manage my next funding round?

Once you secure capital, our integrated platform helps you manage it effectively. Rho provides business banking, corporate cards, and automated bill pay, giving you full control over your new funds from one place.