Top 11 Venture Capital Firms in Portola Valley
For founders raising capital in Portola Valley, we've compiled a list of the 11 most active venture firms to help you connect with potential investors.
Rho Editorial Team

For founders preparing to raise capital, understanding the investors in your immediate area is a critical first step. The venture capital community in Portola Valley, and the surrounding Silicon Valley area, holds significant influence. To help you prepare, our team at Rho has put together this overview of the top firms in the area, giving you a straightforward look at the key investors so you can focus your fundraising efforts effectively.
Rho provides access to business banking, corporate cards, and bill pay — built for startup teams moving fast.
Key Takeaways
- Seeking venture capital funding is about more than just money; it’s about finding a partner who will take an equity stake and help you grow your company.
- Portola Valley is a hub for venture capital, with notable firms like Shasta Ventures, Almaz Capital, Scribble Ventures, and Canvas Ventures actively investing in new companies.
- Once you secure funding, our team at Rho provides the tools to manage it effectively through business banking, corporate cards, and automated bill pay, all in one platform.
Which Portola Valley VC Firms Are Right for Your Stage?
Whether your company is in its early days or preparing for an exit, it’s helpful to know which investors to contact. This overview outlines which Portola Valley VC firms invest at specific stages.
Pre-seed and Seed VC Firms in Portola Valley
Pre-seed and seed funding are the first institutional checks a startup receives, intended to help you move from an idea to a viable product with initial traction. For founders seeking seed funding, Portola Valley has several options, including Scribble Ventures, which focuses on pre-seed through Series A, and Shasta Ventures, which invests in seed and early-stage enterprises.
Early Stage VC Firms in Portola Valley
Early-stage venture capital typically supports companies through Series A and Series B rounds, providing capital to scale operations and grow your customer base. Among the early-stage VC firms in the area are Canvas Ventures, an AI venture firm that also invests in fintech and digital health, and Tenaya Capital, which backs a range of technology-driven companies.
Late Stage VC Firms in Portola Valley
Late-stage funding is designed for mature companies preparing for major expansion, a potential acquisition, or an IPO. Firms providing this type of venture capital financing include Western Technology Investment, which specializes in acquisition financing, and Emergent Medical Partners, a life sciences firm focused on healthcare companies.
It's also worth noting that some venture capital firms, such as Almaz Capital and XSeed Capital, invest across multiple stages from seed to late-stage growth.
Below is a closer look at the top VC firms in Portola Valley, California, including key details about their investment stages, sector focus, portfolio highlights, and what makes each firm a compelling choice for founders.
1. Shasta Ventures

Founded in 2004, Shasta Ventures is a venture capital firm that provides capital to enterprise startups. They concentrate on seed and early-stage companies, helping them build foundational products and establish market fit.
The firm maintains a clear focus on enterprise technology, backing companies that build software for businesses. Their approach centers on partnering with founders at the earliest stages to help shape product and go-to-market strategy.
If you are a founder building an enterprise software company and are looking for a partner for your seed or Series A round, Shasta Ventures could be a strong fit. Their experience is most relevant for teams building for business customers.
- Investment stages: Seed and early-stage venture
- Industries of focus: Enterprise technology
- Founded: 2004
- Portfolio size: Over 430 investments
- Track record: 99 exits
You can refer to their website here.
2. Almaz Capital

Almaz Capital is a venture capital firm that backs companies in the information technology sector. They have a history of investing in early-stage startups and supporting their growth.
The firm is notable for its flexible investment strategy, providing capital from seed rounds all the way to late-stage venture. This multi-stage approach suggests they are prepared to partner with companies for the long term.
If you are a founder in the IT space looking for a financial partner that can support you across multiple growth phases, Almaz Capital may be a good fit. Their model is suited for teams seeking consistent backing from early development through to scaling.
- Investment stages: Seed, early-stage, and late-stage venture
- Industries of focus: Information technology
- Founded: 2008
- Portfolio size: 100 investments
- Track record: 20 exits
You can refer to their website here.
3. Scribble Ventures

Scribble Ventures is an early-stage investment fund that concentrates on companies from the pre-seed stage through Series A. Founded in 2020, the firm provides initial capital to help new businesses get off the ground and find their footing.
The firm shows a clear interest in impact investing and financial services, signaling a focus on companies that aim for both financial returns and positive social outcomes. Their specific attention to pre-seed, seed, and Series A rounds indicates they prefer to partner with founders from the very beginning.
If you are a founder at the earliest stages of building your company, particularly in fintech or with an impact-driven mission, Scribble Ventures could be a suitable partner. Their model is designed for teams needing their first institutional check to build and validate their product.
- Investment stages: Pre-seed through Series A
- Industries of focus: Financial Services, Impact Investing
- Founded: 2020
- Portfolio size: 98 investments
- Track record: 7 exits
You can refer to their website here.
4. Canvas Ventures

Canvas Ventures is a venture capital firm that invests in early-stage companies, primarily at the Series A and B stages. They provide capital to startups operating in fintech, digital health, and artificial intelligence.
The firm maintains a clear focus on these specific high-growth sectors, suggesting a deep expertise in their target markets. Their concentration on Series A and B rounds indicates they specialize in helping companies scale after finding initial product-market fit.
If you are a founder in fintech, digital health, or AI and are preparing for a Series A or B round, Canvas Ventures is worth considering. Their sector-specific approach is well-suited for teams looking for investors with relevant operational experience.
- Investment stages: Early-stage venture (Series A and B)
- Industries of focus: Fintech, digital health, AI
- Founded: 2013
- Portfolio size: 105 investments
- Track record: 17 exits
You can refer to their website here.
5. Western Technology Investment

Western Technology Investment is a long-standing venture capital firm, founded in 1980, that provides financing to companies with established revenue. They specialize in offering acquisition financing, supporting businesses through significant growth milestones.
The firm is notable for its flexible financing structures, which include debt and equity across all stages from seed to late-stage. Their focus is primarily on the finance, financial services, and FinTech sectors.
If your company is already generating revenue and you are exploring financing options beyond traditional equity, WTI could be a good match. They are particularly suited for founders considering an acquisition or needing structured debt to grow.
- Investment stages: Seed, early-stage, late-stage, private equity, debt, and grant
- Industries of focus: Finance, FinTech, and Financial Services
- Founded: 1980
- Portfolio size: Over 400 investments
- Track record: 144 exits
You can refer to their website here.
6. Hanover Technology Investment Management

Hanover Technology Investment Management provides capital to technology companies in their initial growth phases. They focus on businesses they believe have the potential to make a significant impact in their respective markets.
The firm invests across multiple stages, from seed to late-stage venture, indicating they are prepared to support companies throughout their lifecycle. Their focus on "transformative" technology suggests a preference for businesses with ambitious, market-changing ideas.
If you are a founder of a technology company seeking a long-term financial partner, Hanover may be a good fit. Their multi-stage approach is well-suited for teams that want consistent backing as they scale.
- Investment stages: Seed, early-stage, and late-stage venture
- Industries of focus: Technology
- Founded: 2013
- Portfolio size: 36 investments
- Track record: 1 exit
You can refer to their website here.
7. Tenaya Capital

Tenaya Capital is a venture capital firm that invests in a broad set of technology-driven companies. They provide funding to support businesses as they grow and scale their operations.
The firm invests across multiple stages, from early-stage rounds to late-stage growth and private equity. This flexibility suggests they are equipped to support companies throughout their entire lifecycle, with a stated focus on enterprise software.
If you are a founder of an enterprise software company looking for a partner for the long run, Tenaya Capital could be a good fit. Their model is designed for teams that value having a consistent investor from the early days through to maturity.
- Investment stages: Early-stage venture, late-stage venture, and private equity
- Industries of focus: Enterprise Software
- Founded: 2009
- Portfolio size: 186 investments
- Track record: 68 exits
You can refer to their website here.
8. XSeed Capital

XSeed Capital is a venture firm that provides funding to entrepreneurs building unique technology companies. They focus on helping founders create businesses that have a distinct advantage in the market.
The firm invests across multiple stages, from seed to late-stage venture, showing they are prepared to support companies throughout their growth. Their emphasis on "differentiated technology" suggests they value businesses with a strong technical or market advantage.
If you are a founder building a technology company with a clear competitive edge, XSeed Capital could be a good match. Their model is well-suited for teams seeking a long-term financial partner that can invest from the earliest stages through to maturity.
- Investment stages: Seed, early-stage, and late-stage venture
- Industries of focus: Finance, Financial Services, and Venture Capital
- Founded: 2006
- Portfolio size: 94 investments
- Track record: 19 exits
You can refer to their website here.
9. Partner Ventures

Partner Ventures operates as a "secondary direct" venture capital fund, meaning they purchase equity from existing shareholders. Their primary role is to provide liquidity to founders, executives, and early investors in established private companies.
The firm’s approach is notable because they do not invest primary capital directly into a company for growth. Instead, they specialize in discreet and efficient transactions that allow individuals to realize value from their holdings.
If you are a founder or early employee at a high-growth company and want to sell some of your equity, Partner Ventures may be a good fit. They are not a source for a company's main funding round but rather a partner for shareholder liquidity.
- Investment focus: Secondary direct investments providing liquidity to shareholders
- Investment stages: Early-stage and late-stage venture
- Founded: 2009
- Portfolio size: 63 investments
- Track record: 7 exits
- Notable portfolio companies: SpaceX, Palantir, and Slack
You can refer to their website here.
10. Emergent Medical Partners

Emergent Medical Partners is a life sciences investment firm that provides capital to medical device and healthcare companies. They are based in California and focus on businesses within the medical sector.
The firm’s flexible investment approach is a key characteristic, as they provide debt, venture, and private equity financing. This multi-stage capability, combined with a clear focus on biotechnology and medical companies, signals deep expertise in the healthcare industry.
If you are a founder in the medical or biotech space seeking a financial partner for the long term, this firm could be a strong match. Their model is built to support companies through various stages of growth, from initial funding to maturity.
- Investment stages: Debt, early-stage, late-stage, and private equity
- Industries of focus: Biotechnology, Medical, and Financial Services
- Founded: 2006
- Portfolio size: 36 investments
- Track record: 14 exits
You can refer to their website here.
11. Synergy Life Science Partner

Synergy Life Science Partner is a venture capital firm that finances early-stage companies developing medical devices and combination products. They provide capital to businesses within the life sciences sector.
The firm’s specific concentration on medical devices and combination products indicates a deep knowledge of this regulated industry. Their investment model spans from early-stage venture to private equity, suggesting they can support a company's financial needs over the long term.
If you are a founder of an early-stage medical device company, Synergy Life Science Partner could be a strong financial partner. Their model is well-suited for teams that need an investor with specific industry expertise and the capacity for follow-on funding.
- Investment stages: Early-stage venture, late-stage venture, and private equity
- Industries of focus: Medical device and combination products
- Founded: 2006
- Portfolio size: 20 investments
- Track record: 6 exits
You can refer to their website here.
What This Tells Us About Portola Valley's VC Scene
The venture capital scene in Portola Valley is remarkably well-balanced, offering opportunities for companies across various stages. While you can find firms that specialize in initial funding rounds, many investors here are prepared to support businesses from seed to late-stage growth. This suggests a market where founders can find long-term financial partners, not just a single check.
Sector-wise, there is a strong focus on enterprise technology and financial services, alongside a notable cluster of life sciences and medical device investors. For you as a founder, the key takeaway is the importance of targeted outreach. The diversity of firms means there is likely a good fit for your company, provided you align your stage and industry with the right investor’s expertise.
Raise Confidently with Rho
Fundraising requires significant time and focus, so a targeted list of relevant investors is invaluable. It allows you to direct your energy toward the firms most likely to be a good fit for your company.
After a successful fundraise, the next step is putting that capital to work. If you’ve just raised, Rho can help you set up your financial stack in minutes.
Our platform provides the tools to manage your new capital efficiently. We offer business banking, corporate cards, and bill pay, all in one place to support your startup's growth.
FAQs about Venture Capital Firms in Portola Valley
What do SaaS venture capital firms in Portola Valley look for?
They typically seek a strong founding team, a clear product-market fit, and a scalable business model. You should be prepared to demonstrate early traction and a well-defined go-to-market strategy to capture their interest and secure a meeting.
Are there many biotech venture capital firms in Portola Valley?
Yes, Portola Valley has a notable concentration of life sciences and biotech investors, including Emergent Medical Partners and Synergy Life Science Partner. These firms specialize in funding medical device, healthcare, and biotechnology companies at various growth stages.
How should I approach early-stage VC firms in Portola Valley?
A warm introduction from a trusted contact in their network is often most effective. If you do not have a mutual connection, a concise and personalized email explaining your business and its fit for their portfolio can also work.
What is the difference between seed funding and Series A venture capital firms?
Seed funding firms provide the initial capital to help you build a product and find market fit. Series A firms invest later, providing capital to scale your operations and grow your customer base once you have proven traction.
How can Rho help after I secure venture capital financing for my startup?
Once you've raised capital, our platform helps you manage it. We provide business banking, corporate cards, and automated bill pay in one place. You can get started with Rho and set up your financial operations quickly.