Top 15 Venture Capital Firms Investing in Healthcare

For founders in healthcare, biotech, or the life sciences, finding the right investor is a critical step. Knowing which venture capital firms specialize in your field—from digital health to medical devices—can make a significant difference when you prepare to raise capital.

To help you identify potential partners, our team at Rho created this overview of top VC firms active in the health sector. This guide offers a quick summary of relevant investors, allowing you to focus your fundraising efforts more effectively.

Rho provides access to business banking, corporate cards, and bill pay — built for startup teams moving fast.

Key Takeaways

• Securing venture funding provides healthcare startups with the critical capital needed for long research cycles, clinical trials, and bringing new treatments or technologies to market.

• Prominent firms like Deerfield Management, Silversmith Capital Partners, New Enterprise Associates, and Vivo Capital are notable backers in the healthcare sector, investing in companies across biotech, medical devices, and digital health.

• Once you've secured funding, Rho helps you manage and deploy your new capital efficiently with integrated tools like fast business banking, corporate cards, and automated bill pay.

Which VC Firms in Healthcare Are Right for Your Stage?

Whether your company is in its early stages or preparing for an exit, connecting with the right investors is key. Below is a quick look at which healthcare VC firms invest at each stage.

Pre-seed and Seed VC Firms in Healthcare

Pre-seed and seed funding are the earliest forms of capital, typically used to validate an idea, build a minimum viable product (MVP), and make initial hires. For founders at this initial stage, firms like Springbank Collective, 25madison, and Creative Ventures are known for backing new companies.

Early Stage VC Firms in Healthcare

Early-stage funding, which includes Series A and B rounds, helps startups with a proven product achieve commercial traction and scale their operations. Prominent early-stage healthcare venture capital firms, including Boston-based Third Rock Ventures and LRVHealth, focus on helping life science and healthtech startups grow.

Late Stage VC Firms in Healthcare

Late-stage capital is for established companies looking to expand into new markets, make acquisitions, or prepare for an initial public offering (IPO). Investors active in this space include New Enterprise Associates (NEA), a firm with a long history in technology and healthcare, and Deerfield Management, which invests across venture, growth, and public equity.

Once you secure funding from any of these partners, our team at Rho can help you manage and deploy your new capital efficiently with integrated tools for business banking, corporate cards, and automated bill pay.

It's also worth noting that many firms, such as Silversmith Capital Partners and Maverick Ventures, invest across multiple stages from seed to growth.

To help you identify the right investors, we've compiled a list of top VC firms in the healthcare sector. For each firm, you'll find details on their investment stages, geographic focus, and what makes them a compelling choice for founders.

1. Deerfield Management

Deerfield Management is an investment firm dedicated to advancing healthcare through capital, information, and philanthropy. Based in New York, the firm has been active since 1994, supporting companies across the healthcare spectrum.

A key aspect of Deerfield's strategy is its broad investment range, backing companies from seed stage all the way to post-IPO. Their portfolio includes notable companies like Nuvalent, an oncology biotech that completed a $165 million IPO, and Viatris, a global drugmaker that is among the firm's largest equity holdings.

This firm is a strong potential partner for healthcare founders seeking a long-term relationship with an investor that can provide support across multiple growth phases. Their focus on information and philanthropy suggests they offer resources beyond just financial backing.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture, Post-IPO

• Industries of focus: Health Care, Health Insurance, Information Services

• Location: New York, NY

• Founded: 1994

• Notable investments: Nuvalent, Viatris, Neurocrine Biosciences, Centene Corporation

• Firm type: Private Equity, Venture Capital

You can refer to their website here.

2. Silversmith Capital Partners

Based in Boston, Silversmith Capital Partners is a growth equity firm that partners with founders of profitable, growing companies in the technology and healthcare sectors. Since its founding in 2015, the firm has focused on providing capital to support scalable businesses.

Silversmith has a clear affinity for product-led SaaS companies, having backed several that grew to billion-dollar valuations. Its portfolio includes marketing automation platform ActiveCampaign and no-code website builder Webflow. The firm often makes the first institutional investment in a company, supporting founders who have successfully bootstrapped their businesses to a significant scale.

This firm is an excellent match for founders of capital-efficient tech or health-tech companies who have already achieved product-market fit and are seeking a partner for their next phase of growth. Once you secure that growth capital, Rho’s integrated platform helps you manage and deploy it with tools for business banking, corporate cards, and automated bill pay.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture, Private Equity

• Industries of focus: Health Care, Information Technology, Information Services

• Location: Boston, MA

• Founded: 2015

• Notable investments: ActiveCampaign, Appfire, impact.com, Webflow, SurveyMonkey (Momentive)

You can refer to their website here.

3. New Enterprise Associates

New Enterprise Associates (NEA) is one of the oldest and most established venture capital firms, investing in both technology and healthcare companies since 1977. With deep roots in Silicon Valley, they have a global presence and a long history of backing industry-defining businesses.

A key characteristic of NEA is its ability to support companies across their entire lifecycle, from early venture rounds through to post-IPO stages. The firm has a track record of backing major companies, including oncology drug developer Tesaro (acquired by GSK) and AI platform Databricks.

NEA is a great fit for founders in technology or healthcare who are seeking a long-term financial partner that can provide capital at multiple stages of growth. Once you secure that funding, our team at Rho can help you manage it with integrated tools for banking, cards, and payments.

• Investment stages: Early Stage Venture, Late Stage Venture, Post-IPO, Debt

• Industries of focus: Health Care, Technology, Consumer, Financial Services

• Location: Menlo Park, CA

• Founded: 1977

• Notable investments: Databricks, Tesaro, Acadia Pharmaceuticals, 3Com

• Firm type: Venture Capital

You can refer to their website here.

4. Vivo Capital

Vivo Capital is a global investment firm focused exclusively on the healthcare sector, managing approximately $5.8 billion in assets. Since 1996, they have backed companies developing new therapies and technologies across the globe.

A defining feature of Vivo Capital is its focus on companies with late-stage clinical assets, often supporting them through FDA approval and commercial launch. Many of their portfolio companies, like Avadel Pharmaceuticals and Geron Corporation, have reached significant regulatory milestones, shifting from clinical development to commercial status.

This firm is a great fit for founders of life science companies with products in later stages of clinical development. For teams preparing for regulatory submissions and commercialization, Vivo's experience could be invaluable.

Once you secure funding, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.

• Investment stages: Early Stage Venture, Late Stage Venture, Post-IPO, Private Equity

• Industries of focus: Health Care

• Location: Palo Alto, CA

• Founded: 1996

• Notable investments: Soleno Therapeutics, Verona Pharma, Geron Corporation, Avadel Pharmaceuticals

• Firm type: Private Equity, Venture Capital

You can refer to their website here.

5. Maverick Ventures

Maverick Ventures is the venture capital arm of Maverick Capital, investing from its San Francisco office. The firm focuses on backing early-stage companies in both the healthcare and technology sectors.

A key characteristic is the firm's track record of backing companies through to major exits. Their portfolio includes One Medical, acquired by Amazon, and Hims & Hers Health, a telemedicine brand that went public via SPAC.

This firm is a strong match for founders of early-stage healthcare and tech companies that have a clear path toward a large-scale exit. Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture

• Industries of focus: Health Care, Cyber Security, Generative AI

• Location: San Francisco, CA

• Founded: 2015

• Notable investments: Coupang, One Medical, Hims & Hers Health, Cityblock Health

• Firm type: Venture Capital

You can refer to their website here.

6. SV Health Investors

SV Health Investors is a Boston-based firm that has been investing in biotechnology and healthcare companies since 1993. They provide capital across the life sciences, from medical devices to biotech.

A defining characteristic is their ability to support companies through their entire lifecycle, from seed funding to post-IPO stages. Their portfolio shows a history of backing companies to major exits, including telehealth platform Amwell and drug developer Achillion Pharmaceuticals, which was acquired by Alexion.

This firm is a strong match for founders in biotech or healthtech seeking a long-term partner that can fund growth at any stage. Once you secure that funding, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture, Post-IPO, Private Equity, Debt

• Industries of focus: Biotechnology, Health Care, Life Science, Medical Device

• Location: Boston, MA

• Founded: 1993

• Notable investments: American Well (Amwell), Insulet Corporation, Achillion Pharmaceuticals, Sutro Biopharma

• Firm type: Private Equity, Venture Capital

You can refer to their website here.

7. Versant Ventures

Versant Ventures has been investing in the healthcare sector since 1999, providing capital from early venture stages through to post-IPO. Based in Menlo Park, the firm focuses on building companies that address significant medical needs.

The firm has a strong record of backing foundational companies in life sciences, often from their earliest stages through to major exits. Their portfolio includes gene-editing pioneer CRISPR Therapeutics and Audentes Therapeutics, a gene-therapy company acquired for $3 billion.

Versant is an ideal partner for founders in biotech and life sciences with ambitious, science-driven ideas. If your company requires long-term support to navigate clinical development and commercialization, their deep expertise could be a great fit.

Once you secure funding from a partner like Versant, our team at Rho can help you manage and deploy your new capital efficiently with integrated tools for business banking, corporate cards, and automated bill pay.

• Investment stages: Early Stage Venture, Late Stage Venture, Post-IPO

• Industries of focus: Health Care, Life Science

• Location: Menlo Park, CA

• Founded: 1999

• Notable investments: CRISPR Therapeutics, Jazz Pharmaceuticals, Inari Medical, RayzeBio, Audentes Therapeutics

• Firm type: Venture Capital

You can refer to their website here.

8. Pfizer

While known as a global biopharmaceutical giant, Pfizer also operates a corporate venture capital arm, Pfizer Ventures. From its New York headquarters, the firm invests in emerging companies that are developing breakthrough medicines and technologies.

Pfizer Ventures focuses on companies with pioneering science, backing firms like Arrakis Therapeutics, which develops drugs that bind to RNA, and Artios Pharma, an oncology company focused on DNA damage response. Their portfolio shows a pattern of supporting companies through significant milestones, including Rhythm Pharmaceuticals' successful IPO.

This firm is an excellent match for founders of biotech and pharmaceutical startups whose work aligns with Pfizer's strategic interests. A partnership offers not just capital but also access to the deep scientific and commercial expertise of a major industry player.

Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.

• Investment stages: Venture, Private Equity

• Industries of focus: Biotechnology, Health Care, Medical, Pharmaceutical, Precision Medicine

• Location: New York, NY

• Founded: 1849

• Notable investments: Arrakis Therapeutics, Artios Pharma, Rhythm Pharmaceuticals, Medtronic

• Firm type: Corporate Venture Capital, Venture Capital

You can refer to their website here.

9. Redmile Group

Redmile Group is a San Francisco-based investment firm focused on the healthcare sector. Since 2007, they have provided capital to companies through venture, growth, and crossover investing.

A key part of Redmile's strategy is its flexibility, investing from early venture stages all the way to post-IPO. Their portfolio features companies that have achieved major milestones, such as BioNTech, the pioneer behind a COVID-19 vaccine, and digital health unicorn Virta Health.

Redmile is a strong match for founders of healthcare companies who are on a trajectory toward the public markets or a major commercial launch. Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.

• Investment stages: Early Stage Venture, Late Stage Venture, Post-IPO, Private Equity

• Industries of focus: Health Care

• Location: San Francisco, CA

• Founded: 2007

• Notable investments: BioNTech, Virta Health, Science 37, ADC Therapeutics

• Firm type: Hedge Fund, Private Equity, Venture Capital

You can refer to their website here.

10. 25madison

25madison is a New York-based venture platform that both incubates new business ideas and invests in early-stage startups. The firm is structured to support companies from inception through their next phase of growth.

A key feature is its dual role as an incubator and a venture capital investor, signaling a hands-on approach to building companies. Their portfolio is diverse, including public-safety app Citizen and avatar-tech unicorn Genies, reflecting a focus on high-growth consumer and tech businesses.

This firm is an excellent match for founders at the earliest stages who are seeking an active partner to help build their company. Their model is particularly well-suited for teams that can benefit from operational support to get a new idea off the ground.

Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.

• Investment stages: Seed, Early Stage Venture

• Industries of focus: Health Care, FinTech, Consumer Applications, Incubators

• Location: New York, NY

• Founded: 2018

• Notable investments: Citizen, Genies, Hut 8, TMRW Sports Group, Landa

• Firm type: Incubator, Venture Capital

You can refer to their website here.

11. LRVHealth

LRVHealth is a Boston-based venture capital firm that has operated with an “Inside Healthcare” approach since 2000. The team is composed of experienced healthcare investors, operators, and advisors who provide deep industry knowledge.

A defining characteristic is the firm's track record of backing companies to significant exits, including patient-intake platform Phreesia’s IPO and the acquisition of Current Health by Best Buy. This demonstrates their ability to support companies from development through to major market validation, such as the acquisition of oncology-focused Carevive by Health Catalyst.

This firm is a strong match for founders in health tech or medical devices who value hands-on support from investors with deep operational and industry experience. Their focus on seed to late-stage venture makes them a solid partner for long-term growth.

Once you secure funding, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture

• Industries of focus: Health Care, Medical Device, Enterprise, Security

• Location: Boston, MA

• Founded: 2000

• Notable investments: Phreesia, Current Health, GetWellNetwork, Carevive, Diameter Health

• Firm type: Venture Capital

You can refer to their website here.

12. Third Rock Ventures

Third Rock Ventures is a Boston-based firm that has been investing in high-growth life science companies since 2007. They focus on building businesses around science that can create new standards of care.

A key part of their approach is backing companies with groundbreaking science and guiding them to major exits. Their portfolio includes gene-editing pioneer Editas Medicine, which they incubated, and Sage Therapeutics, which developed the first FDA-approved therapy for postpartum depression.

This firm is an excellent partner for founders in biotech with ambitious, science-driven ideas that require long-term support. Once you secure funding, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.

• Investment stages: Seed, Early Stage Venture, Late Stage Venture, Post-IPO

• Industries of focus: Biotechnology, Health Care, Medical Device

• Location: Boston, MA

• Founded: 2007

• Notable investments: Sage Therapeutics, Editas Medicine, bluebird bio, Global Blood Therapeutics

• Firm type: Venture Capital

You can refer to their website here.

13. Springbank Collective

Springbank Collective is an early-stage investment firm focused on building infrastructure to support women and working families. Based in New York, the firm provides seed and early-stage capital to companies in sectors like healthcare, financial services, and consumer tech.

A defining characteristic is their thematic focus on the "care economy" and solutions that create a more equitable future. Their portfolio includes Chief, a private network for women executives that became a unicorn, and Wellthy, a digital caregiving platform.

This firm is an ideal partner for founders whose businesses directly address the needs of modern families, whether in health, finance, or workplace tools. Once funding is secured, Rho’s integrated financial tools—including business banking, corporate cards, and automated bill pay—help startups manage and deploy capital efficiently.

• Investment stages: Seed, Early Stage Venture

• Industries of focus: Health Care, Financial Services, Consumer, Women's

• Location: New York, NY

• Founded: 2019

• Notable investments: Chief, Wellthy, Promise, Copper

• Firm type: Venture Capital, Syndicate

You can refer to their website here.

14. TMV

TMV is an early-stage investment firm based in New York that focuses on "the future of living well." Since 2016, they have backed companies across sectors like healthcare, fintech, and education that aim to solve systemic challenges.

The firm has a history of supporting purpose-driven companies through to major exits, including medical-apparel brand FIGS and primary-care provider Cityblock Health. Their portfolio reflects a clear focus on businesses that improve daily life and well-being.

TMV is a great fit for early-stage founders building companies with a strong mission, particularly in consumer health and wellness. Once you secure funding, our team at Rho can help you manage it with integrated tools for banking, cards, and payments.

• Investment stages: Seed, Early Stage Venture, Secondary Market

• Industries of focus: Health Care, FinTech, Education, Logistics, Transportation

• Location: New York, NY

• Founded: 2016

• Notable investments: Cityblock Health, FIGS, Casper Sleep, ClassTag

• Firm type: Venture Capital

You can refer to their website here.

15. Creative Ventures

Based in Oakland, Creative Ventures is a deep tech venture firm that backs early-stage companies tackling major global challenges. The firm invests from seed to early venture rounds, focusing on businesses built on scientific and engineering breakthroughs.

A key part of their strategy is investing in "deep tech" to solve problems in sectors like healthcare, climate, and construction. Their portfolio includes AI-powered retail tech company Caper, acquired by Instacart, and quantum-computing startup Bleximo, which is focused on challenges like drug discovery.

This firm is a great fit for founders with a background in science or engineering who are building companies to solve complex, real-world problems. Once you secure that early-stage funding, our team at Rho can help you manage it with integrated tools for banking, cards, and payments.

• Investment stages: Seed, Early Stage Venture

• Industries of focus: Deep Tech, Health Care, Robotics, Clean Energy, Construction

• Location: Oakland, CA

• Founded: 2016

• Notable investments: Caper (acquired by Instacart), Sense Photonics (acquired by Ouster), Bleximo

• Firm type: Venture Capital

You can refer to their website here.

What This Tells Us About The VC Scene for Healthcare Companies

This overview shows that the funding environment for healthcare companies is both deep and varied. You’ll find investors ready to support businesses at every point, from early-stage specialists like 25madison to firms like Deerfield Management that invest across a company's entire lifecycle. This suggests a well-balanced market where capital is available for different growth phases.

Geographically, investors are concentrated in major hubs like Boston, New York, and the Bay Area, which can help you focus your fundraising efforts. The mix of traditional VCs, corporate partners, and incubators also means you have options for finding the right kind of partnership. Once you secure that funding, our team at Rho can help you manage and deploy your new capital efficiently with integrated tools for business banking, corporate cards, and automated bill pay.

Raise Confidently with Rho

Raising capital requires significant time and focus, which is why starting with a targeted list of investors is so important. We hope this guide gives you a clear starting point for your outreach.

Once your round is closed, the work of managing that capital begins. If you’ve just raised, Rho can help you set up your financial stack in minutes.

Our platform integrates business banking, corporate cards, and automated bill pay to help you deploy your new funding with control. This lets you focus on growing your business, not on managing finances.

FAQs about Venture Capital Firms Focused on Healthcare

Which biotech venture capital firms are in Boston?

Boston is a major hub for life sciences. Firms like Third Rock Ventures, SV Health Investors, and LRVHealth are based there, often backing companies in biotech and medical devices from their earliest stages through to commercialization.

Which healthcare venture capital firms are in the Bay Area?

The Bay Area is a key center for health and tech investors. Firms like New Enterprise Associates, Vivo Capital, and Maverick Ventures are active there, providing capital to companies across healthcare, from biotech to digital health platforms.

Are there prominent healthcare venture capital firms in Europe?

Yes, Europe has a growing number of specialized healthcare VCs. Many US-based firms also have a strong presence there, investing in biotech, medtech, and digital health startups across the continent, particularly in hubs like London and Switzerland.

What do early-stage healthcare VC firms look for?

Early-stage investors typically look for a strong founding team, a clear scientific or technological advantage, and a large addressable market. They want to see a credible plan for reaching key milestones, like clinical trials or product-market fit.

How can Rho help my startup manage its finances?

Once funding is secured, Rho’s integrated financial tools help you deploy capital efficiently. Our platform offers business banking, corporate cards, and automated bill pay so you can focus on growth. Get started with Rho today.